I used Comic Sans MS for my experiment. In the second line I flipped the I and the S around and upside down then changed the P and H to caps while taking the L, U, and C out of caps. I reflected the D. The third line I reflected it horizontally. I believe that readability is always important. If you can't read it then how would I get the message to you. The only time I would say that readability doesn't matter is if you were making a jumble puzzle for some one. I do believe what we did here could be a very valuable design tool as long as you don't over do it. You ever read those type of puzzles where the letters are all jumbled but somehow you can still read the whole paragraph with ease and the paragraph is usually is explaining why that's possible? I that is a perfect example of this design tool and how it can be used to grab a readers attention. For example see the link.